Aminopyrazine carboxamide

For research use only. Not for therapeutic Use.

  • CAT Number: I022032
  • CAS Number: 32587-10-3
  • Molecular Formula: C5H6N4O
  • Molecular Weight: 138.13
  • Purity: 98%
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Aminopyrazine carboxamide(CAT: I022032) is a pyrazolone compound known for its multifaceted properties. This compound exhibits analgesic, anti-inflammatory, and antipyretic characteristics. Its analgesic attribute suggests the potential in alleviating pain, while its anti-inflammatory property implies a role in mitigating inflammatory responses. Furthermore, its antipyretic potential indicates the ability to lower fever. These combined properties point to a compound with potential therapeutic applications in managing pain, inflammation, and fever-related conditions, making aminopyrazine carboxamide of interest for pharmacological research and drug development endeavors.


Catalog Number I022032
CAS Number 32587-10-3
Synonyms

Aminopyrazine carboxamide

Molecular Formula C5H6N4O
Purity 98%
Solubility Soluble in DMSO
Appearance Solid powder
Storage Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
IUPAC Name 3-Aminopyrazine-2-carboxamide
InChI 1S/C5H6N4O/c6-4-3(5(7)10)8-1-2-9-4/h1-2H,(H2,6,9)(H2,7,10)
InChIKey SFSMATGDLFHTHE-UHFFFAOYSA-N
SMILES c1cnc(c(n1)C(=O)N)N
Reference

1: Pijls KE, de Vries H, Nikkessen S, Bast A, Wodzig WK, Koek GH. Critical appraisal of 13C breath tests for microsomal liver function: aminopyrine revisited. Liver Int. 2014 Apr;34(4):487-94. doi: 10.1111/liv.12451. Epub 2014 Jan 16. Review. PubMed PMID: 24428683.
2: Park JA, Zhang D, Kim SK, Cho SH, Cho SM, Yi H, Shim JH, Kim JS, Abd El-Aty AM, Shin HC. Simultaneous determination of aminopyrine and antipyrine in porcine muscle, milk, and eggs using liquid chromatography with tandem mass spectrometry. J Sep Sci. 2015 Dec;38(23):4048-54. doi: 10.1002/jssc.201500920. Epub 2015 Nov 3. PubMed PMID: 26434939.
3: Uetrecht JP, Ma HM, MacKnight E, McClelland R. Oxidation of aminopyrine by hypochlorite to a reactive dication: possible implications for aminopyrine-induced agranulocytosis. Chem Res Toxicol. 1995 Mar;8(2):226-33. PubMed PMID: 7766805.

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