For research use only. Not for therapeutic Use.
Aminoquinol triphosphate may be useful in the treatment of acute necrotising cutaneous leishmaniasis.
| Catalog Number | I022041 |
| CAS Number | 3653-53-0 |
| Synonyms | Aminochinol triphosphate, Aminoquinol triphosphate |
| Molecular Formula | C26H40Cl2N3O12P3 |
| Purity | 98% |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | 1,4-Pentanediamine, N(sup 4)-(7-chloro-2-(2-(2-chlorophenyl)ethenyl)-4-quinolinyl)-N(sup 1),N(sup 1)-diethyl-, phosphate (1:3) |
| InChI | 1S/C26H31Cl2N3.3H3O4P/c1-4-31(5-2)16-8-9-19(3)29-26-18-22(14-12-20-10-6-7-11-24(20)28)30-25-17-21(27)13-15-23(25)26;3*1-5(2,3)4/h6-7,10-15,17-19H,4-5,8-9,16H2,1-3H3,(H,29,30);3*(H3,1,2,3,4)/b14-12+ |
| InChIKey | NHNXMYYNFQHZMQ-XPGLNUPKSA-N |
| SMILES | C(CC[C@@H](C)Nc1cc(C=Cc2ccccc2Cl)nc2cc(Cl)ccc12)N(CC)CC.P(=O)(O)(O)O.P(=O)(O)(O)O.P(=O)(O)(O)O |
| Reference | 1: Labesse G, Ferrari D, Chen ZW, Rossi GL, Kuusk V, McIntire WS, Mathews FS. Crystallographic and spectroscopic studies of native, aminoquinol, and monovalent cation-bound forms of methylamine dehydrogenase from Methylobacterium extorquens AM1. J Biol Chem. 1998 Oct 2;273(40):25703-12. PubMed PMID: 9748238. |
