Amiodarone-d10 hydrochloride

• CAT Number: S000503
• CAS Number: 1261393-77-4
• Molecular Formula: C25H20D10ClI2NO3
• Molecular Weight: 691.83
• Purity: ≥95%
• IUPAC Name: [4-[2-[bis(1,1,2,2,2-pentadeuterioethyl)amino]ethoxy]-3,5-diiodophenyl]-(2-butyl-1-benzofuran-3-yl)methanone;hydrochloride
• InChI: InChI=1S/C25H29I2NO3.ClH/c1-4-7-11-22-23(18-10-8-9-12-21(18)31-22)24(29)17-15-19(26)25(20(27)16-17)30-14-13-28(5-2)6-3;/h8-10,12,15-16H,4-7,11,13-14H2,1-3H3;1H/i2D3,3D3,5D2,6D2
• InChIKey: ITPDYQOUSLNIHG-XYDKDKLNSA-N
• SMILES: CCCCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC(=C(C(=C3)I)OCCN(CC)CC)I.Cl

Amiodarone-d10 hydrochloride（Cat No.:S000503） is a deuterated form of amiodarone hydrochloride, where ten hydrogen atoms are replaced with deuterium. Amiodarone is a potent and widely used antiarrhythmic medication for treating and preventing various types of cardiac dysrhythmias, including atrial fibrillation and ventricular tachycardia. The incorporation of deuterium into amiodarone-d10 enhances its metabolic stability, allowing for more precise pharmacokinetic studies. These studies are crucial for understanding the drug’s metabolism and excretion, helping to optimize dosing regimens and reduce potential side effects, thereby improving patient safety and treatment efficacy in cardiac care.