For research use only. Not for therapeutic Use.
Amiphenazole(Cat No.:I022046)is a drug with central nervous system effects, primarily used as a respiratory stimulant. It works by enhancing respiratory drive, making it useful in managing conditions where respiratory depression is a concern, such as during anesthesia recovery or in cases of drug-induced respiratory suppression. Amiphenazole is thought to act on the brainstem to stimulate the respiratory centers, improving oxygen intake and carbon dioxide expulsion. However, due to its potential side effects, including tachycardia and nervousness, it is typically used in controlled medical settings where respiratory support is needed.
Catalog Number | I022046 |
CAS Number | 490-55-1 |
Synonyms | Amiphenazole; Amiphenazol; Daftazol; DAPT; Daptazile; Daptazole; DHA-245; Dizol; Fenamizol; Phenamizol; Phenamizole; UNII-7ZJ8PWY0XD; |
Molecular Formula | C9H9N3S |
Purity | 98% |
Solubility | Soluble in DMSO |
Appearance | Solid powder |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
IUPAC Name | 5-phenyl-1,3-thiazole-2,4-diamine |
InChI | InChI=1S/C9H9N3S/c10-8-7(13-9(11)12-8)6-4-2-1-3-5-6/h1-5H,10H2,(H2,11,12) |
InChIKey | UPOYFZYFGWBUKL-UHFFFAOYSA-N |
SMILES | C1=CC=C(C=C1)C2=C(N=C(S2)N)N |
Reference | 1: Lehmann KA, Huttarsch H, Schroeder B, Zech D. [Development of continuous monitoring of spontaneous respiration in the postoperative phase. 2. Cutaneous oxygen and carbon dioxide partial pressures following i.v. bolus application of fentanyl, buprenorphine, naloxone and amiphenazole in healthy adult subjects]. Anaesthesist. 1992 Apr;41(4):192-8. German. PubMed PMID: 1350432. |