For research use only. Not for therapeutic Use.
Amlodipine Besylate is a long-acting calcium channel blocker, used to lower blood pressure and prevent chest pain.<br>Amlodipine besylate reduces the declines in p85aPI3K, phosphorylated Akt, phosphorylated GSK-3β, heat-shock transcription factor-1, and Bcl-2 induced by H(2) O(2) , as well as the increases in cyclooxygenase-2, cytosolic cytochrome c, cleaved caspase 9, and cleaved caspase 3 in neuronal cell.<br>Amlodipine besylate significantly decreases average indirect systolic blood pressure measurements from 198 mmHg to 155 mmHg in the cats. Amlodipine besylate appears to be a safe and effective oral treatment for systemic hypertension in cats when used chronically once daily as a single agent.
| Catalog Number | A000944 |
| CAS Number | 111470-99-6 |
| Synonyms | NA |
| Molecular Formula | C20H25ClN2O5.C6H6O3S |
| Purity | ≥95% |
| Target | Neuronal Signaling |
| Solubility | >26.1mg/mL in DMSO |
| Storage | 3 years -20C powder |
