Amlodipine Diethyl Ester

• CAT Number: R047667
• CAS Number: 140171-65-9
• Molecular Formula: C21H27ClN2O5
• Molecular Weight: 422.906
• Purity: ≥95%
• Synonyms: 2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic Acid 3,5-Diethyl Ester; 3-Ethyl 5-Ethyl 4-(2-Chlorophenyl)-6-methyl-2-[[2- [(2-aminoethoxy)methyl]-1,4-dihydropyridine-3,5-dicarboxylate
• Storage: -20°C
• IUPAC Name: diethyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
• InChI: InChI=1S/C21H27ClN2O5/c1-4-28-20(25)17-13(3)24-16(12-27-11-10-23)19(21(26)29-5-2)18(17)14-8-6-7-9-15(14)22/h6-9,18,24H,4-5,10-12,23H2,1-3H3
• InChIKey: BGGLOZPVAWMSEB-UHFFFAOYSA-N
• SMILES: CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OCC)COCCN)C

Amlodipine Diethyl Ester is a derivative of amlodipine, a calcium channel blocker commonly used in cardiovascular research. This esterified form is primarily used as an intermediate in chemical synthesis and pharmaceutical studies. Amlodipine Diethyl Ester helps in understanding the pharmacological properties of amlodipine derivatives, particularly their effects on calcium ion influx in vascular smooth muscle and cardiac tissues. Its role in modulating blood pressure and reducing cardiac workload makes it a valuable compound for studying hypertension and angina. Researchers use this compound to explore new drug development strategies for cardiovascular disorders.