For research use only. Not for therapeutic Use.
Amlodipine Orotate(CAT: I022069) is a salt form of amlodipine, a well-known calcium channel blocker used primarily in cardiovascular research. By inhibiting the influx of calcium ions into vascular smooth muscle and cardiac cells, it effectively reduces vascular resistance and myocardial oxygen demand. The orotate salt form enhances solubility and stability, making it suitable for various experimental applications. Amlodipine Orotate is widely utilized in studies on hypertension, angina, and other cardiovascular conditions. Its high purity and reliability ensure consistent results, making it a valuable tool for researchers investigating calcium channel modulation and potential therapeutic approaches for cardiovascular diseases.
| CAS Number | 914941-70-1 |
| Synonyms | Amlodipine orotate |
| Molecular Formula | C25H29ClN4O9 |
| Purity | 98% |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | 3,5-Pyridinedicarboxylic acid, 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester, compd. with 1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidinecarboxylic acid (1:1) |
| InChI | 1S/C20H25ClN2O5.C5H4N2O4/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21;8-3-1-2(4(9)10)6-5(11)7-3/h5-8,17,23H,4,9-11,22H2,1-3H3;1H,(H,9,10)(H2,6,7,8,11) |
| InChIKey | DBGOBQCYSPDGNR-UHFFFAOYSA-N |
| SMILES | CCOC(=O)C1=C(COCCN)NC(=C(C1c2ccccc2Cl)C(=O)OC)C.OC(=O)C3=CC(=O)NC(=O)N3 |
