AMN082

• CAT Number: I002241
• CAS Number: 97075-46-2
• Molecular Formula: C28H30Cl2N2
• Molecular Weight: 465.46
• Purity: ≥95%
• Synonyms: AMN 082; AMN-082; AMN082;N,N/’-bis[di(phenyl)methyl]ethane-1,2-diamine
• Target: Neuronal Signaling
• Solubility: Soluble in DMSO
• Storage: Desiccate at +4C
• IUPAC Name: N,N'-dibenzhydrylethane-1,2-diamine;dihydrochloride
• InChI: InChI=1S/C28H28N2.2ClH/c1-5-13-23(14-6-1)27(24-15-7-2-8-16-24)29-21-22-30-28(25-17-9-3-10-18-25)26-19-11-4-12-20-26;;/h1-20,27-30H,21-22H2;2*1H
• InChIKey: YRQCDCNQANSUPB-UHFFFAOYSA-N
• SMILES: C1=CC=C(C=C1)C(C2=CC=CC=C2)NCCNC(C3=CC=CC=C3)C4=CC=CC=C4.Cl.Cl

AMN082(CAT: I002241) is a potent and selective positive allosteric modulator and activator of group II and III metabotropic glutamate receptors (mGluRs), particularly targeting mGluR7. By enhancing the activity of these presynaptic receptors, AMN082 regulates glutamate release and modulates synaptic transmission. It has been extensively studied for its potential therapeutic applications in neurological and psychiatric disorders, including anxiety, depression, and epilepsy. AMN082 provides a valuable tool for investigating the physiological roles of mGluR II and III in synaptic plasticity, neuroprotection, and the development of targeted treatments for glutamate-mediated pathologies.