For research use only. Not for therapeutic Use.
Amorolfine (CAT: C000561) is a potent antifungal agent that belongs to the class of morpholine derivatives. Its mode of action involves interfering with the biosynthesis of ergosterol, a key component of fungal cell membranes, leading to membrane disruption and subsequent inhibition of fungal growth. Amorolfine’s pharmacologic action against fungal pathogens makes it an effective topical treatment option for various cutaneous fungal infections, such as onychomycosis (fungal nail infections) and tinea (ringworm) infections.
| Catalog Number | C000561 |
| CAS Number | 78613-35-1 |
| Synonyms | rel-(2R,6S)-4-[3-[4-(1,1-Dimethylpropyl)phenyl]-2-methylpropyl]-2,6-dimethylmorpholine; Amorolfine; Loceryl; Ro 14-4767; Ro 14-4767/000; cis- 4-[3-[4-(1,1-Dimethylpropyl)phenyl]-2-methylpropyl]-2,6-dimethyl-morpholine |
| Molecular Formula | C₂₁H₃₅NO |
| Purity | ≥95% |
| Solubility | Chloroform (Slightly), Methanol (Slightly) |
| Appearance | Colourless Oil |
| Storage | 4°C, Inert atmosphere |
| Reference | Rosen, T. et al.: J. Drugs Dermatol., 14, 48 (2015); |
