Amotosalen free base

• CAT Number: I022111
• CAS Number: 161262-29-9
• Molecular Formula: C17H19NO4
• Molecular Weight: 301.34
• Purity: 98%
• Synonyms: Amotosalen; Amotosalen free base, S-59; S 59; S59.
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 7H-Furo(3,2-g)(1)benzopyran-7-one, 3-((2-aminoethoxy)methyl)-2,5,9-trimethyl-
• InChI: InChI=1S/C17H19NO4/c1-9-6-15(19)22-16-10(2)17-13(7-12(9)16)14(11(3)21-17)8-20-5-4-18/h6-7H,4-5,8,18H2,1-3H3
• InChIKey: FERWCFYKULABCE-UHFFFAOYSA-N
• SMILES: O=C1C=C(C)C2=CC3=C(OC(C)=C3COCCN)C(C)=C2O1

Amotosalen free base (Cat No.: I022111) is a synthetic psoralen compound used in pathogen reduction technology for blood and plasma products. It intercalates into DNA and RNA and, upon UVA light activation, forms covalent crosslinks, preventing replication of viruses, bacteria, and parasites. Amotosalen is widely used in blood transfusion safety to reduce the risk of transfusion-transmitted infections. Its selective targeting of nucleic acids without affecting essential blood components makes it a valuable tool in improving the safety of blood products for clinical use.