Amoxicillin trihydrate

• CAT Number: I004317
• CAS Number: 61336-70-7
• Molecular Formula: C16H19N3O5S • 3H2O
• Molecular Weight: 419.40
• Purity: ≥95%
• Synonyms: (2S,5R,6R)-6-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, trihydrate
• Target: Antibacterial
• Solubility: 10 mM in DMSO
• Storage: Room temperature
• IUPAC Name: (2S,5R,6R)-6-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;trihydrate
• InChI: InChI=1S/C16H19N3O5S.3H2O/c1-16(2)11(15(23)24)19-13(22)10(14(19)25-16)18-12(21)9(17)7-3-5-8(20)6-4-7;;;/h3-6,9-11,14,20H,17H2,1-2H3,(H,18,21)(H,23,24);3*1H2/t9-,10-,11+,14-;;;/m1.../s1
• InChIKey: MQXQVCLAUDMCEF-CWLIKTDRSA-N
• SMILES: CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](C3=CC=C(C=C3)O)N)C(=O)O)C.O.O.O

Amoxicillin Trihydrate（Cat No.:I004317）is a widely used penicillin-class antibiotic effective against a range of bacterial infections, including respiratory, urinary, and ear infections. This form provides enhanced stability and absorption, making it suitable for oral administration. Amoxicillin Trihydrate works by inhibiting bacterial cell wall synthesis, leading to bacterial death, and is especially effective against Gram-positive and some Gram-negative bacteria. Known for its mild side-effect profile, it is frequently prescribed for both adults and children. Its efficacy and safety make it essential in clinical and pharmaceutical research, especially for combating common bacterial infections.

Reference

1. http://en.wikipedia.org/wiki/Amoxicillin
2.Expert Opin Drug Saf. 2009 Jan;8(1):111-8. doi: 10.1517/14740330802527984.Amoxicillin and amoxicillin plus clavulanate: a safety review.Salvo F(1), De Sarro A, Caputi AP, Polimeni G.

Despite the considerable number of newer antibacterials made available over the past decades, amoxicillin, alone or in combination with clavulanic acid, still accounts among the most widely used antibacterial agents. Although they are often considered 'twin drugs', they are different both in terms of antibacterial activities and of safety profile. It is well documented that the clavulanate component may cause adverse reactions by itself, thus exposing patients to further, and sometimes undue, risks. Although amoxicillin/clavulanate should be considered as an alternative agent only for the treatment of resistant bacteria, evidence shows that it is often used also when a narrow-spectrum antibiotic would have been just as effective. This prescription habit may have serious consequences in terms of patients' safety, as well as in terms of the development of bacterial resistance.