Amphotericin B Methyl Ester 90percent

For research use only. Not for therapeutic Use.

  • CAT Number: R056009
  • CAS Number: 36148-89-7
  • Molecular Formula: C48H75NO17
  • Molecular Weight: 938.12
  • Purity: ≥95%
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Amphotericin B Methyl Ester(Cat No.:R056009)is a derivative of Amphotericin B, an antifungal polyene macrolide. This methyl ester modification reduces its hydrophilicity while retaining antifungal activity, making it a valuable tool for studying structure-activity relationships in antifungal compounds. Amphotericin B Methyl Ester disrupts fungal cell membranes by binding to ergosterol, causing pore formation and cell death. It is commonly used in biochemical research to explore membrane interactions and drug delivery systems. Its 90% purity ensures consistency and reliability for experimental and pharmaceutical studies in antifungal drug development.


Catalog Number R056009
CAS Number 36148-89-7
Synonyms

Amphotericin B Monomethyl Ester;

Molecular Formula C48H75NO17
Purity ≥95%
Target HIV
Storage Store at -20C
IUPAC Name methyl (1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-[(2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylate
InChI InChI=1S/C48H75NO17/c1-28-18-16-14-12-10-8-6-7-9-11-13-15-17-19-35(65-47-45(59)42(49)44(58)31(4)64-47)25-39-41(46(60)62-5)38(55)27-48(61,66-39)26-34(52)23-37(54)36(53)21-20-32(50)22-33(51)24-40(56)63-30(3)29(2)43(28)57/h6-19,28-39,41-45,47,50-55,57-59,61H,20-27,49H2,1-5H3/b7-6+,10-8+,11-9+,14-12+,15-13+,18-16+,19-17+/t28-,29-,30-,31+,32+,33+,34-,35-,36+,37+,38-,39-,41+,42-,43+,44+,45-,47-,48+/m0/s1
InChIKey UAZIZEMIKKIBCA-TYVGYKFWSA-N
SMILES C[C@H]1/C=C/C=C/C=C/C=C/C=C/C=C/C=C/[C@@H](C[C@H]2[C@@H]([C@H](C[C@](O2)(C[C@H](C[C@H]([C@@H](CC[C@H](C[C@H](CC(=O)O[C@H]([C@@H]([C@@H]1O)C)C)O)O)O)O)O)O)O)C(=O)OC)O[C@H]3[C@H]([C@H]([C@@H]([C@H](O3)C)O)N)O

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