For research use only. Not for therapeutic Use.
Amphotericin B Methyl Ester(Cat No.:R056009)is a derivative of Amphotericin B, an antifungal polyene macrolide. This methyl ester modification reduces its hydrophilicity while retaining antifungal activity, making it a valuable tool for studying structure-activity relationships in antifungal compounds. Amphotericin B Methyl Ester disrupts fungal cell membranes by binding to ergosterol, causing pore formation and cell death. It is commonly used in biochemical research to explore membrane interactions and drug delivery systems. Its 90% purity ensures consistency and reliability for experimental and pharmaceutical studies in antifungal drug development.
Catalog Number | R056009 |
CAS Number | 36148-89-7 |
Synonyms | Amphotericin B Monomethyl Ester; |
Molecular Formula | C48H75NO17 |
Purity | ≥95% |
Target | HIV |
Storage | Store at -20C |
IUPAC Name | methyl (1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-[(2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylate |
InChI | InChI=1S/C48H75NO17/c1-28-18-16-14-12-10-8-6-7-9-11-13-15-17-19-35(65-47-45(59)42(49)44(58)31(4)64-47)25-39-41(46(60)62-5)38(55)27-48(61,66-39)26-34(52)23-37(54)36(53)21-20-32(50)22-33(51)24-40(56)63-30(3)29(2)43(28)57/h6-19,28-39,41-45,47,50-55,57-59,61H,20-27,49H2,1-5H3/b7-6+,10-8+,11-9+,14-12+,15-13+,18-16+,19-17+/t28-,29-,30-,31+,32+,33+,34-,35-,36+,37+,38-,39-,41+,42-,43+,44+,45-,47-,48+/m0/s1 |
InChIKey | UAZIZEMIKKIBCA-TYVGYKFWSA-N |
SMILES | C[C@H]1/C=C/C=C/C=C/C=C/C=C/C=C/C=C/[C@@H](C[C@H]2[C@@H]([C@H](C[C@](O2)(C[C@H](C[C@H]([C@@H](CC[C@H](C[C@H](CC(=O)O[C@H]([C@@H]([C@@H]1O)C)C)O)O)O)O)O)O)O)C(=O)OC)O[C@H]3[C@H]([C@H]([C@@H]([C@H](O3)C)O)N)O |