Ampicillin sodium

• CAT Number: A001058
• CAS Number: 69-52-3
• Molecular Formula: C16H18N3O4S • Na
• Molecular Weight: 371.40
• Purity: ≥95%
• Target: Antibiotic
• Solubility: Soluble in DMSO > 10 mM
• Storage: 3 years -20C powder
• IUPAC Name: sodium;(2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
• InChI: InChI=1S/C16H19N3O4S.Na/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8;/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23);/q;+1/p-1/t9-,10-,11+,14-;/m1./s1
• InChIKey: KLOHDWPABZXLGI-YWUHCJSESA-M
• SMILES: CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](C3=CC=CC=C3)N)C(=O)[O-])C.[Na+]

Ampicillin Sodium（Cat No.:A001058）is a broad-spectrum, beta-lactam antibiotic effective against both Gram-positive and some Gram-negative bacteria. It functions by inhibiting bacterial cell wall synthesis, leading to cell lysis and death. The sodium salt form increases its solubility, allowing for intravenous and intramuscular administration, which is essential for treating serious infections like respiratory, urinary tract, and gastrointestinal infections. Ampicillin Sodium is widely used in clinical and research settings, including bacterial culture media to select for ampicillin-resistant organisms. Its effectiveness and stability make it a mainstay in antibiotic therapy.

Reference

Guzmán, Flavio, MD. /Beta Lactams Antibiotics (penicillins and Cephalosporins) Mechanism of Action.” Medical Pharmacology. Pharmacology Corner, 29 Nov. 2008. Web. 21 Aug. 2012.Pitout JD, Sanders CC, Sanders WE Jr. Antimicrobial resistance with focus on beta-lactam resistance in gram-negative bacilli. Am J Med 1997; 103:51.