Ampiroxicam

• CAT Number: A000266
• CAS Number: 99464-64-9
• Molecular Formula: C20H21N3O7S
• Molecular Weight: 447.46
• Purity: ≥95%
• Synonyms: 99464-64-9; Flucam; Ampiroxicamum; CP 65703; Ampiroxicamum [Latin]
• Target: COX
• Solubility: Soluble in DMSO > 10 mM
• Storage: -20°C
• IUPAC Name: ethyl 1-[[2-methyl-1,1-dioxo-3-(pyridin-2-ylcarbamoyl)-1lambda6,2-benzothiazin-4-yl]oxy]ethyl carbonate
• InChI: 1S/C20H21N3O7S/c1-4-28-20(25)30-13(2)29-18-14-9-5-6-10-15(14)31(26,27)23(3)17(18)19(24)22-16-11-7-8-12-21-16/h5-13H,4H2,1-3H3,(H,21,22,24)
• InChIKey: LSNWBKACGXCGAJ-UHFFFAOYSA-N
• SMILES: CCOC(=O)OC(C)OC1=C(N(S(=O)(=O)C2=CC=CC=C21)C)C(=O)NC3=CC=CC=N3

Ampiroxicam (A000266) is a nonsteroidal anti-inflammatory drug (NSAID) derived from the oxicam class, used for its analgesic and anti-inflammatory effects. It works by inhibiting cyclooxygenase (COX) enzymes, particularly COX-2, which are responsible for producing prostaglandins involved in inflammation and pain. Ampiroxicam is primarily used to manage conditions such as osteoarthritis, rheumatoid arthritis, and acute pain. Though effective, it may cause side effects like gastrointestinal discomfort, renal issues, and cardiovascular risks, especially with long-term use or high doses.