AMPK activator 13

• CAT Number: I040287
• Molecular Formula: C23H21BrN2O
• Molecular Weight: 421.33
• Purity: ≥95%
• Synonyms: 5-(4-methylphenyl)-2-[1-[(3-methylphenyl)methyl]pyridin-1-ium-3-yl]-1,3-oxazole;bromide
• InChI: InChI=1S/C23H21N2O.BrH/c1-17-8-10-20(11-9-17)22-14-24-23(26-22)21-7-4-12-25(16-21)15-19-6-3-5-18(2)13-19;/h3-14,16H,15H2,1-2H3;1H/q+1;/p-1
• InChIKey: RZXBFSPJLVWWQP-UHFFFAOYSA-M
• SMILES: CC1=CC=C(C=C1)C2=CN=C(O2)C3=C[N+](=CC=C3)CC4=CC=CC(=C4)C.[Br-]

AMPK activator 13 is a potent activator of AMPK. AMPK activator 13 inhibits mitotic clonal expansion of 3T3-L1 cells by activating AMPK pathway and enhances cell mitochondrial oxygen consumption rate. AMPK activator 13 can be used in study obesity[1].

Reference

[1]. Mishra T, et al. Anti-adipogenic action of a novel oxazole derivative through activation of AMPK pathway. Eur J Med Chem. 2023 Oct 20;262:115895.
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