Amrubicin

• CAT Number: I000423
• CAS Number: 110267-81-7
• Molecular Formula: C25H25NO9
• Molecular Weight: 483.47
• Purity: ≥95%
• Synonyms: (7S,9S)-9-acetyl-9-amino-7-[(2S,4S,5R)-4,5-dihydroxyoxan-2-yl]oxy-6,11-dihydroxy-8,10-dihydro-7H-tetracene-5,12-dione
• Target: Topoisomerase
• Solubility: DMSO:30mg/mL
• Storage: Store at -20°C

Amrubicin(CAT: I000423), also known as SM-5887, is a novel anthracycline derivative that is used for the treatment of bladder carcinoma. Anthracyclines are a class of chemotherapeutic agents commonly used in cancer treatment due to their ability to inhibit DNA replication and cell division. Amrubicin has shown efficacy in the treatment of bladder carcinoma, a type of cancer that affects the bladder lining. It works by interfering with the DNA in cancer cells, leading to their death and slowing down tumor growth. However, it is important to consult a healthcare professional for accurate and specific information about the use of Amrubicin for bladder carcinoma and its potential side effects.

Reference

[1]. Ohmori, H., T. Tsushima, and K. Kobashi, [Experimental studies on intravesical instillation of SM-5887, a novel anthracycline derivative for treatment of bladder carcinoma]. Gan To Kagaku Ryoho, 1996. 23(5): p. 601-6.

[2]. Tsushima, K., et al., [A phase II study of SM-5887 for advanced gastric cancer]. Gan To Kagaku Ryoho, 1991. 18(7): p. 1151-4.