AN-12-H5 intermediate-1

• CAT Number: I040146
• CAS Number: 254882-14-9
• Molecular Formula: C12H21NO5
• Molecular Weight: 259.30
• Purity: ≥95%
• Synonyms: 1-O-tert-butyl 2-O-methyl (2S,4S)-4-hydroxypiperidine-1,2-dicarboxylate
• InChI: InChI=1S/C12H21NO5/c1-12(2,3)18-11(16)13-6-5-8(14)7-9(13)10(15)17-4/h8-9,14H,5-7H2,1-4H3/t8-,9-/m0/s1
• InChIKey: RNMVWSAJMIKMDY-IUCAKERBSA-N
• SMILES: CC(C)(C)OC(=O)N1CCC(CC1C(=O)OC)O

AN-12-H5 intermediate-1 ((2S,4S)-1-tert-butyl 2-methyl-4-hydroxypiperidine-1,2-dicarboxylate) is an intermediate of the viral inhibitor AN-12-H5 (HY-120900) and can be used to synthesize Antibody-Drug Conjugates (ADCs).

Reference

[1]. AN-12-H5 shows no inhibitory effect on PI4KB activity and only moderate inhibitory effects on PI 3-kinase activity[1].
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