For research use only. Not for therapeutic Use.
AN-3485 is a benzoxaborole analog, Toll-Like Receptor(TLR) inhibitor with IC50 values ranging from 18 to 580 nM.
| Catalog Number | I019991 |
| CAS Number | 1213827-99-6 |
| Synonyms | [3-chloro-4-[(1-hydroxy-3H-2,1-benzoxaborol-6-yl)oxy]phenyl]methanamine |
| Molecular Formula | C14H13BClNO3 |
| Purity | ≥95% |
| InChI | InChI=1S/C14H13BClNO3/c16-13-5-9(7-17)1-4-14(13)20-11-3-2-10-8-19-15(18)12(10)6-11/h1-6,18H,7-8,17H2 |
| InChIKey | ZBLBFNKPCNPVLW-UHFFFAOYSA-N |
| SMILES | B1(C2=C(CO1)C=CC(=C2)OC3=C(C=C(C=C3)CN)Cl)O |
| Reference | [1]. Dong C, et al. Inhibition of Toll-like receptor-mediated inflammation in vitro and in vivo by a novelbenzoxaborole. J Pharmacol Exp Ther. 2013 Feb;344(2):436-46. |
