For research use only. Not for therapeutic Use.
α-<wbr></wbr>Lipoic acid is a cyclic disulfide antioxidant that interconverts with its reduced dithiol form. It is an essential cofactor for decarboxylation reactions of the citric acid cycle and acts as a general antioxidant. AN-<wbr></wbr>7 is a more lipophilic analog of α-<wbr></wbr>lipoic acid with enhanced potency and 1.5-<wbr></wbr>fold increased maximal capacity to stimulate glucose transport into myocytes. This identifies the analogs of lipoic acid as potential new treatments for diabetes.
| Catalog Number | R010142 |
| CAS Number | 691410-93-2 |
| Synonyms | 3-(5-[1,2]dithiolan-3yl-pentanoylamino)-propyl]-amide |
| Molecular Formula | C19H34N2O2S4 |
| Purity | ≥95% |
| Storage | -20°C |
| IUPAC Name | 5-(dithiolan-3-yl)-N-[3-[5-(dithiolan-3-yl)pentanoylamino]propyl]pentanamide |
| InChI | InChI=1S/C19H34N2O2S4/c22-18(8-3-1-6-16-10-14-24-26-16)20-12-5-13-21-19(23)9-4-2-7-17-11-15-25-27-17/h16-17H,1-15H2,(H,20,22)(H,21,23) |
| InChIKey | QGUXZRFEKWOQQL-UHFFFAOYSA-N |
| SMILES | C1CSSC1CCCCC(=O)NCCCNC(=O)CCCCC2CCSS2 |
| Reference | 1.Biewenga, G.P.,Haenen, G.R.M.M., and Bast, A. The pharmacology of the antioxidant lipoic acid. General Pharmacology 29(3), 315-331 (1997). |
