Angiopeptin TFA

• CAT Number: I044304
• CAS Number: 2478421-60-0
• Molecular Formula: C58H73F6N11O14S2
• Molecular Weight: 1326.39
• Purity: ≥95%
• Synonyms: (2S)-6-amino-N-[(2S)-1-[[(2R)-1-[[(2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]-2-[[(2R)-2-[[(2S)-2-[[(2R)-2-[[(2R)-2-amino-3-naphthalen-2-ylpropanoyl]amino]-3-sulfanylpropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]hexanamide;2,2,2-trifluoroacetic acid
• InChI: InChI=1S/C54H71N11O10S2.2C2HF3O2/c1-29(2)45(54(75)63-44(28-77)53(74)65-46(30(3)66)47(57)68)64-49(70)40(14-8-9-21-55)59-51(72)42(25-35-26-58-39-13-7-6-12-37(35)39)61-50(71)41(24-31-16-19-36(67)20-17-31)60-52(73)43(27-76)62-48(69)38(56)23-32-15-18-33-10-4-5-11-34(33)22-32;2*3-2(4,5)1(6)7/h4-7,10-13,15-20,22,26,29-30,38,40-46,58,66-67,76-77H,8-9,14,21,23-25,27-28,55-56H2,1-3H3,(H2,57,68)(H,59,72)(H,60,73)(H,61,71)(H,62,69)(H,63,75)(H,64,70)(H,65,74);2*(H,6,7)/t30-,38-,40+,41+,42-,43+,44+,45+,46+;;/m1../s1
• InChIKey: PLVCOVWXYIMTNV-XCNZXRHRSA-N
• SMILES: C[C@H]([C@@H](C(=O)N)NC(=O)[C@H](CS)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](CC1=CNC2=CC=CC=C21)NC(=O)[C@H](CC3=CC=C(C=C3)O)NC(=O)[C@H](CS)NC(=O)[C@@H](CC4=CC5=CC=CC=C5C=C4)N)O.C(=O)(C(F)(F)F)O.C(=O)(C(F)(F)F)O

Angiopeptin TFA（Cat No.:I044304）is a synthetic cyclic peptide derived from somatostatin, known for its potent anti-proliferative effects on vascular smooth muscle cells. It functions primarily as an inhibitor of intimal hyperplasia and has been studied for its potential in preventing restenosis following angioplasty or vascular grafting. Angiopeptin exerts its effects by binding somatostatin receptors, thereby modulating growth factor signaling and cellular proliferation. The TFA (trifluoroacetate) form refers to its purification as a trifluoroacetate salt, enhancing stability and solubility. It is widely used in cardiovascular and vascular injury research.