Angiotensin III, human, mouse TFA

• CAT Number: I042704
• Molecular Formula: C48H67F3N12O11
• Molecular Weight: 1045.11
• Purity: ≥95%
• Synonyms: (2S)-2-[[(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid;2,2,2-trifluoroacetic acid
• InChI: InChI=1S/C46H66N12O9.C2HF3O2/c1-5-27(4)38(57-40(61)33(21-29-15-17-31(59)18-16-29)53-42(63)37(26(2)3)56-39(60)32(47)13-9-19-51-46(48)49)43(64)54-34(23-30-24-50-25-52-30)44(65)58-20-10-14-36(58)41(62)55-35(45(66)67)22-28-11-7-6-8-12-28;3-2(4,5)1(6)7/h6-8,11-12,15-18,24-27,32-38,59H,5,9-10,13-14,19-23,47H2,1-4H3,(H,50,52)(H,53,63)(H,54,64)(H,55,62)(H,56,60)(H,57,61)(H,66,67)(H4,48,49,51);(H,6,7)/t27-,32-,33-,34-,35-,36-,37-,38-;/m0./s1
• InChIKey: KUKUOXUOOSIHED-BZDVFTEGSA-N
• SMILES: CC[C@H](C)[C@@H](C(=O)N[C@@H](CC1=CN=CN1)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CC3=CC=CC=C3)C(=O)O)NC(=O)[C@H](CC4=CC=C(C=C4)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCN=C(N)N)N.C(=O)(C(F)(F)F)O

Angiotensin III, human, mouse TFA (Cat No.:I042704) is a synthetic peptide derivative of angiotensin II, a key regulator of blood pressure and fluid balance. This compound acts by binding to angiotensin receptors, influencing vasoconstriction and aldosterone secretion. Angiotensin III is often used in research to study the renin-angiotensin system and its role in hypertension, cardiovascular diseases, and kidney function. The TFA salt form enhances stability and solubility, making it suitable for experimental purposes in both human and mouse models. It offers insights into potential therapeutic approaches for managing cardiovascular and renal disorders.