Ani9

For research use only. Not for therapeutic Use.

  • CAT Number: I011371
  • CAS Number: 356102-14-2
  • Molecular Formula: C17H17ClN2O3
  • Molecular Weight: 332.78
  • Purity: ≥95%
Inquiry Now

Ani9 is a potent and selective transmembrane protein 16A (TMEM16A, Anoctamin-1) blocker with IC50 at 77 nM. Ani9 can be applied to the study of cancer and other diseases[1][2].


Catalog Number I011371
CAS Number 356102-14-2
Synonyms

2-(4-chloro-2-methylphenoxy)-N-[(E)-(2-methoxyphenyl)methylideneamino]acetamide

Molecular Formula C17H17ClN2O3
Purity ≥95%
InChI InChI=1S/C17H17ClN2O3/c1-12-9-14(18)7-8-15(12)23-11-17(21)20-19-10-13-5-3-4-6-16(13)22-2/h3-10H,11H2,1-2H3,(H,20,21)/b19-10+
InChIKey KDALDZRKOBJXIE-VXLYETTFSA-N
SMILES CC1=C(C=CC(=C1)Cl)OCC(=O)NN=CC2=CC=CC=C2OC
Reference

[1]. Seo Y, et al. Ani9, A Novel Potent Small-Molecule ANO1 Inhibitor with Negligible Effect on ANO2. PLoS One. 2016 May 24;11(5):e0155771.
 [Content Brief]

[2]. Seo Y, et al. Synthesis and biological evaluation of novel Ani9 derivatives as potent and selective ANO1 inhibitors. Eur J Med Chem. 2018 Dec 5;160:245-255.
 [Content Brief]

Request a Quote