For research use only. Not for therapeutic Use.
AnnH31 is a Dyrk1A inhibitor (IC50: 81 nM). AnnH31 also inhibits MAO-A with an IC50 of 3.2 μM[1].
| Catalog Number | I022211 |
| CAS Number | 241809-12-1 |
| Synonyms | 2-(7-methoxy-1-methylpyrido[3,4-b]indol-9-yl)acetonitrile |
| Molecular Formula | C15H13N3O |
| Purity | ≥95% |
| InChI | InChI=1S/C15H13N3O/c1-10-15-13(5-7-17-10)12-4-3-11(19-2)9-14(12)18(15)8-6-16/h3-5,7,9H,8H2,1-2H3 |
| InChIKey | FCFDJQKAPLIDTQ-UHFFFAOYSA-N |
| SMILES | CC1=NC=CC2=C1N(C3=C2C=CC(=C3)OC)CC#N |
| Reference | [1]. Rüben K, et al. Selectivity Profiling and Biological Activity of Novel β-Carbolines as Potent and Selective DYRK1 Kinase Inhibitors. PLoS One. 2015 Jul 20;10(7):e0132453. |
