ANO1-IN-1

• CAT Number: I043683
• CAS Number: 407587-01-3
• Molecular Formula: C18H28N2O2S
• Molecular Weight: 336.49
• Purity: ≥95%
• IUPAC Name: 6-tert-butyl-2-(2,2-dimethylpropanoylamino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
• InChI: InChI=1S/C18H28N2O2S/c1-17(2,3)10-7-8-11-12(9-10)23-15(13(11)14(19)21)20-16(22)18(4,5)6/h10H,7-9H2,1-6H3,(H2,19,21)(H,20,22)
• InChIKey: QJDASIZKRQHFFS-UHFFFAOYSA-N
• SMILES: CC(C)(C)C1CCC2=C(C1)SC(=C2C(=O)N)NC(=O)C(C)(C)C

ANO1-IN-1（Cat No.:I043683）is a selective inhibitor of the Anoctamin 1 (ANO1) protein, also known as TMEM16A, which functions as a calcium-activated chloride channel. ANO1 is involved in various physiological processes, including smooth muscle contraction, epithelial secretion, and cancer cell migration. By inhibiting ANO1, ANO1-IN-1 has the potential to modulate these processes, making it a promising candidate for the treatment of diseases related to excessive chloride channel activity, such as gastrointestinal disorders, asthma, and certain cancers. Preclinical studies suggest ANO1-IN-1 could offer a novel approach in managing these conditions.