Anti-amyloid agent-1

• CAT Number: I041161
• CAS Number: 1396778-73-6
• Molecular Formula: C21H17F3N2O3
• Molecular Weight: 402.37
• Purity: ≥95%
• Synonyms: 1-[3-[3-(benzylamino)-4-nitrophenyl]phenyl]-2,2,2-trifluoroethanol
• InChI: InChI=1S/C21H17F3N2O3/c22-21(23,24)20(27)17-8-4-7-15(11-17)16-9-10-19(26(28)29)18(12-16)25-13-14-5-2-1-3-6-14/h1-12,20,25,27H,13H2
• InChIKey: ASHWETLKGUZRJW-UHFFFAOYSA-N
• SMILES: C1=CC=C(C=C1)CNC2=C(C=CC(=C2)C3=CC(=CC=C3)C(C(F)(F)F)O)[N+](=O)[O-]

Anti-amyloid agent-1 is a potent anti-amyloid compound and inhibits amyloid aggregation. Anti-amyloid agent-1, compound ex1140 from patent WO2012119035A1, provides a useful method for amyloidosis treatment research[1].

Reference

[1]. Mark A. Reed, et al. Anti-amyloid compounds and methods. Patent WO2012119035A1.