For research use only. Not for therapeutic Use.
Anti-Mouse TIM-3 Antibody (B8.2C12) (Cat No.: I040194) is a monoclonal antibody that specifically targets T-cell immunoglobulin and mucin-domain containing-3 (TIM-3), a cell surface receptor involved in immune regulation. TIM-3 plays a critical role in maintaining immune tolerance and modulating immune responses, particularly in T cells. The B8.2C12 antibody is widely used in immunology research to study immune cell signaling, autoimmunity, and cancer immunotherapy. By blocking TIM-3, it may enhance anti-tumor immunity and restore immune responses in certain disease models.
| Purity | ≥95% |
| Reference | [1]. Shin Foong Ngiow, et al. Anti-TIM3 antibody promotes T cell IFN-γ-mediated antitumor immunity and suppresses established tumors. Cancer Res. 2011, 71, 10. |
