Anti-NASH agent 1

For research use only. Not for therapeutic Use.

  • CAT Number: I040887
  • CAS Number: 2409685-41-0
  • Molecular Formula: C26H33NO4
  • Molecular Weight: 423.54
  • Purity: ≥95%
Inquiry Now

Anti-NASH agent 1 (CAT: I040887) is a derivative of Elafibranor (HY-16737) and a potent agonist of PPAR-α/δ, specifically targeting nonalcoholic steatohepatitis (NASH). In a Methionine-choline deficiency (MCD) induced NASH mouse model, Anti-NASH agent 1 (administered at 3-10 mg/kg for 4 weeks) effectively improves hyperlipidemia, reduces liver fat degeneration, and alleviates liver inflammation. The compound shows low liver toxicity and demonstrates strong liver protection, making it a promising candidate for research and potential therapeutic development in the treatment of NASH.


CAS Number 2409685-41-0
Synonyms

tert-butyl 2-[2,6-dimethyl-4-[(E)-3-[4-(methylamino)phenyl]-3-oxoprop-1-enyl]phenoxy]-2-methylpropanoate

Molecular Formula C26H33NO4
Purity ≥95%
IUPAC Name tert-butyl 2-[2,6-dimethyl-4-[(E)-3-[4-(methylamino)phenyl]-3-oxoprop-1-enyl]phenoxy]-2-methylpropanoate
InChI InChI=1S/C26H33NO4/c1-17-15-19(9-14-22(28)20-10-12-21(27-8)13-11-20)16-18(2)23(17)30-26(6,7)24(29)31-25(3,4)5/h9-16,27H,1-8H3/b14-9+
InChIKey JMNQFYWMYKSSSA-NTEUORMPSA-N
SMILES CC1=CC(=CC(=C1OC(C)(C)C(=O)OC(C)(C)C)C)C=CC(=O)C2=CC=C(C=C2)NC

Request a Quote