For research use only. Not for therapeutic Use.
Antibacterial agent 125 is an antibacterial agent. Antibacterial agent 125 has a potent antimicrobial activity against clinically relevant Gram-positive pathogens with MIC50 values range from 0.25 – 8 μM. Antibacterial agent 125 can be used for the research of antimicrobial resistance[1].
Antibacterial agent 125 has activity against clinically relevant Gram-positive pathogens with MIC50 values from 0.25-8 μM[1].
Antibacterial agent 125 has inhibitory activity against methicillin-resistant Staphylococcus aureus strain without showing cytotoxicity in human cells[1].
Antibacterial agent 125 has high metabolic stability and excellent safety profile[1].
Antibacterial agent 125 not induces resistance after ten passages and has a moderate ability to inhibit the biofilm formation[1].
Catalog Number | I042459 |
CAS Number | 1274611-43-6 |
Synonyms | 2-(3-chlorophenyl)-N-(4-cyanophenyl)acetamide |
Molecular Formula | C15H11ClN2O |
Purity | ≥95% |
InChI | InChI=1S/C15H11ClN2O/c16-13-3-1-2-12(8-13)9-15(19)18-14-6-4-11(10-17)5-7-14/h1-8H,9H2,(H,18,19) |
InChIKey | QUFHIWLHKLGWNH-UHFFFAOYSA-N |
SMILES | C1=CC(=CC(=C1)Cl)CC(=O)NC2=CC=C(C=C2)C#N |
Reference | [1]. Francesca Brunelli, et al. Isocyanides in med chem: A scaffold hopping approach for the identification of novel 4-isocyanophenylamides as potent antibacterial agents against methicillin-resistant Staphylococcusaureus. Eur J Med Chem. 2022 Nov 26;246:114950. |