Antibiotic-202

• CAT Number: I002062
• CAS Number: 1616113-45-1
• Molecular Formula: C35H39NO11
• Molecular Weight: 649.68
• Purity: ≥95%
• Target: Bacterial
• Solubility: DMSO: ≥ 31 mg/mL
• Storage: Store at -20°C
• IUPAC Name: 1-[2,7-bis[2-[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]ethynyl]spiro[fluorene-9,4'-piperidine]-1'-yl]ethanone
• InChI: InChI=1S/C35H39NO11/c1-18(39)36-12-10-35(11-13-36)23-14-19(4-8-25-29(40)33(44)31(42)27(16-37)46-25)2-6-21(23)22-7-3-20(15-24(22)35)5-9-26-30(41)34(45)32(43)28(17-38)47-26/h2-3,6-7,14-15,25-34,37-38,40-45H,10-13,16-17H2,1H3/t25-,26-,27-,28-,29-,30-,31-,32-,33-,34-/m1/s1
• InChIKey: SFHMWDMKUYVSQJ-VECBPBMLSA-N
• SMILES: CC(=O)N1CCC2(CC1)C3=C(C=CC(=C3)C#C[C@@H]4[C@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)C5=C2C=C(C=C5)C#C[C@@H]6[C@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O

Antibiotic-202（Cat No.:I002062）is an experimental antibiotic studied for its broad-spectrum activity against gram-positive and gram-negative bacteria. It functions by targeting bacterial cell wall synthesis, disrupting cell membrane integrity, and inhibiting essential enzymatic processes, leading to bacterial cell death. In research, Antibiotic-202 is valuable for examining mechanisms of action, resistance pathways, and potential therapeutic applications in combating multi-drug-resistant infections. Its efficacy and unique mechanism make it an important candidate in antimicrobial research, aiming to address the growing need for new antibiotics to combat resistant bacterial strains.

Reference

[1]. Ramtohul, Yeeman K, et al. Preparation of mannose derivatives via coupling and click cycloaddition reactions for treating bacterial infections. From PCT Int. Appl. (2014), WO 2014100158 A1 20140626.