Antifungal agent 49

• CAT Number: I041087
• CAS Number: 1414861-21-4
• Molecular Formula: C15H12O4
• Molecular Weight: 256.25
• Purity: ≥95%
• Synonyms: 5-benzoyl-2,3-dihydroxy-6-methylcyclohepta-2,4,6-trien-1-one
• InChI: InChI=1S/C15H12O4/c1-9-7-12(16)15(19)13(17)8-11(9)14(18)10-5-3-2-4-6-10/h2-8H,1H3,(H2,16,17,19)
• InChIKey: LBEOUJODZMOAIF-UHFFFAOYSA-N
• SMILES: CC1=CC(=O)C(=C(C=C1C(=O)C2=CC=CC=C2)O)O

Antifungal agent 49 (Example 112) is an antifungal agent. Antifungal agent 49 is active against Cryptococcus neoformans with a MIC value of 49 μM[1].
Antifungal agent 49 (Example 112) (48 h) shows cytotoxicity with a CC50 of 79 μM in HepDES 19 cells[1].

Reference

[1]. Maureen J. DONLIN, et al. Anti-fungal compounds. Patent. WO2017184752. 2017-10-26.