Antileukinate

• CAT Number: R026780
• CAS Number: 138559-60-1
• Molecular Formula: C45H66N18O7S
• Molecular Weight: 1003.20
• Purity: ≥95%
• Synonyms: N2-Acetyl-L-arginyl-L-arginyl-L-tryptophyl-L-tryptophyl-L-cysteinyl-L-argininamide; IL-8 (inhibitor); 5: PN: US20090131329 PAGE: 7 Claimed Sequence
• Target: Immunology/Inflammation
• Storage: -20°C
• IUPAC Name: (2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-sulfanylpropanoyl]amino]-5-(diaminomethylideneamino)pentanamide
• InChI: InChI=1S/C45H66N18O7S/c1-24(64)58-32(14-7-17-54-44(49)50)38(66)60-33(15-8-18-55-45(51)52)39(67)61-34(19-25-21-56-29-11-4-2-9-27(25)29)40(68)62-35(20-26-22-57-30-12-5-3-10-28(26)30)41(69)63-36(23-71)42(70)59-31(37(46)65)13-6-16-53-43(47)48/h2-5,9-12,21-22,31-36,56-57,71H,6-8,13-20,23H2,1H3,(H2,46,65)(H,58,64)(H,59,70)(H,60,66)(H,61,67)(H,62,68)(H,63,69)(H4,47,48,53)(H4,49,50,54)(H4,51,52,55)/t31-,32-,33-,34-,35-,36-/m0/s1
• InChIKey: FVRBFNYUBYTVIQ-NGTAMTFRSA-N
• SMILES: CC(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CC3=CNC4=CC=CC=C43)C(=O)NC(CS)C(=O)NC(CCCN=C(N)N)C(=O)N

Antileukinate（Cat No.:R026780）is a synthetic peptide and potent inhibitor of CXC chemokine receptor activity, particularly targeting IL-8-mediated responses. It is widely used in research to study inflammatory processes, as it effectively blocks the recruitment of neutrophils and other immune cells to sites of inflammation. This makes Antileukinate valuable in exploring therapeutic strategies for conditions like rheumatoid arthritis, acute respiratory distress syndrome, and other inflammatory diseases. Its specificity and efficacy in modulating immune responses position it as a critical tool in both basic and applied immunology research.