For research use only. Not for therapeutic Use.
Antineoplaston A10（Cat No.:I002419）is a synthetic compound derived from naturally occurring peptides and amino acids, developed as part of Dr. Stanislaw Burzynski’s alternative cancer treatment approach. It is believed to work by targeting and modulating gene expression in cancer cells, promoting cell differentiation and inhibiting abnormal cell growth. Antineoplaston A10 has been studied for its potential anti-cancer effects, particularly in brain cancers like gliomas. However, its efficacy and safety remain controversial, with ongoing debates regarding its clinical benefits, and it has not been widely accepted in mainstream oncology.
| Catalog Number | I002419 |
| CAS Number | 91531-30-5 |
| Synonyms | ANP-A-10; ANPA-10; ANP A 10; ANPA 10;;N-[(3S)-2,6-dioxopiperidin-3-yl]-2-phenylacetamide |
| Molecular Formula | C13H14N2O3 |
| Purity | ≥95% |
| Target | Ras inhibitor |
| Solubility | Soluble in DMSO |
| Storage | 2-8°C |
| IUPAC Name | N-[(3S)-2,6-dioxopiperidin-3-yl]-2-phenylacetamide |
| InChI | InChI=1S/C13H14N2O3/c16-11-7-6-10(13(18)15-11)14-12(17)8-9-4-2-1-3-5-9/h1-5,10H,6-8H2,(H,14,17)(H,15,16,18)/t10-/m0/s1 |
| InChIKey | OQGRFQCUGLKSAV-JTQLQIEISA-N |
| SMILES | C1CC(=O)NC(=O)[C@H]1NC(=O)CC2=CC=CC=C2 |
| Reference | </br>1:Immune modulatory potentials of antineoplaston A-10 in breast cancer patients. Badria F, Mabed M, El-Awadi M, Abou-Zeid L, Al-Nashar E, Hawas S.Cancer Lett. 2000 Aug 31;157(1):57-63. PMID: 10893443 </br>2:Potential utility of antineoplaston A-10 levels in breast cancer. Badria F, Mabed M, Khafagy W, Abou-Zeid L.Cancer Lett. 2000 Jul 3;155(1):67-70. PMID: 10814881 </br>3:The inhibitory effect of the combination of antineoplaston A-10 injection with a small dose of cis-diamminedichloroplatinum on cell and tumor growth of human hepatocellular carcinoma. Tsuda H, Sugihara S, Nishida H, Hara H, Eriguchi N, Ishii K, Sasaki K, Yoshimura S, Tanaka N.Jpn J Cancer Res. 1992 May;83(5):527-31. PMID: 1377669 </br>4:The anticancer effect of antineoplaston A-10 on human breast cancer serially transplanted to athymic mice. Hashimoto K, Koga T, Shintomi Y, Tanaka M, Kakegawa T, Tsuda H, Hara H.Nihon Gan Chiryo Gakkai Shi. 1990 Jan 20;25(1):1-5. PMID: 2157780 </br>5:Inhibitory effect of antineoplaston A-10 on breast cancer transplanted to athymic mice and human hepatocellular carcinoma cell lines. The members of Antineoplaston Study Group. Tsuda H.Kurume Med J. 1990;37(2):97-104. PMID: 2175003 Free Article</br>6:Chemopreventive effect of antineoplaston A-10 on urethane-induced pulmonary neoplasm in mice. Eriguchi N, Hara H, Yoshida H, Nishida H, Nakayama T, Ohishi K, Tsuda H, Inoue S, Ikeda I.Nihon Gan Chiryo Gakkai Shi. 1988 Jul 20;23(7):1560-5. No abstract available. PMID: 3183462 |
