For research use only. Not for therapeutic Use.
Antitubercular agent-30 is an antibacterial agent against Mycobacterium tuberculosis (MIC=50 μg/mL). Antitubercular agent-30 has little cytotoxic effect on murine macrophage cells (LD85=~100 μg/mL)[1].
Antitubercular agent-30 (compound 16) (0.1-100 μg/mL; 18 h) shows no cytotoxic effect on murine macrophage with concentration below 10 μg/mL[1].
| Catalog Number | I041184 |
| CAS Number | 384857-54-9 |
| Synonyms | N-(4-nitrophenyl)-2-thiophen-2-ylacetamide |
| Molecular Formula | C12H10N2O3S |
| Purity | ≥95% |
| InChI | InChI=1S/C12H10N2O3S/c15-12(8-11-2-1-7-18-11)13-9-3-5-10(6-4-9)14(16)17/h1-7H,8H2,(H,13,15) |
| InChIKey | BOASBEGFXYCEPO-UHFFFAOYSA-N |
| SMILES | C1=CSC(=C1)CC(=O)NC2=CC=C(C=C2)[N+](=O)[O-] |
| Reference | [1]. Silva Lourenço MC, et al. Synthesis and biological evaluation of N-(aryl)-2-thiophen-2-ylacetamides series as a new class of antitubercular agents. Bioorg Med Chem Lett. 2007 Dec 15;17(24):6895-8. |
