Antiviral agent 17

• CAT Number: I043694
• CAS Number: 158227-81-7
• Molecular Formula: C11H14N4O4
• Molecular Weight: 266.25
• Purity: ≥95%
• Synonyms: (2S,3R,4S,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-(hydroxymethyl)oxolane-3,4-diol
• InChI: InChI=1S/C11H14N4O4/c12-11-6-2-1-5(15(6)14-4-13-11)10-9(18)8(17)7(3-16)19-10/h1-2,4,7-10,16-18H,3H2,(H2,12,13,14)/t7-,8-,9-,10+/m1/s1
• InChIKey: IGZFWIAREXANMY-KYXWUPHJSA-N
• SMILES: C1=C(N2C(=C1)C(=NC=N2)N)C3C(C(C(O3)CO)O)O

Antiviral agent 17 (Compound 4) is an anti-infection agent. Antiviral agent 17 retains its antiviral effect in a human replicon assay (EC50 = 0.015 μM). Antiviral agent 17 results in good antiviral activity against murine norovirus. Antiviral agent 17 has the potential for the research of infectious and malignant diseases[1].

Reference

[1]. Li Q, et al. Anti-norovirus activity of C7-modified 4-amino-pyrrolo[2,1-f][1,2,4]triazine C-nucleosides. Eur J Med Chem. 2020 Jun 1;195:112198.
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