Antrodin A

• CAT Number: I022278
• CAS Number: 656830-24-9
• Molecular Formula: C19H22O4
• Molecular Weight: 314.381
• Purity: 98%
• Synonyms: Camphorataanhydride A; Antrodin A; AdA
• Target: Disease Research Fields
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 2,5-Furandione, 3-(4-((3-methyl-2-butenyl)oxy)phenyl)-4-(2-methylpropyl)-
• InChI: InChI=1S/C19H22O4/c1-12(2)9-10-22-15-7-5-14(6-8-15)17-16(11-13(3)4)18(20)23-19(17)21/h5-9,13H,10-11H2,1-4H3
• InChIKey: ZXIUCXGVUOQMSH-UHFFFAOYSA-N
• SMILES: O=C(C(C1=CC=C(OC/C=C(C)/C)C=C1)=C2CC(C)C)OC2=O

Antrodin A(CAT: I022278), with the chemical name (5S,6R,7R,8R)-6,7,8-trihydroxy-2,3,4,5-tetrahydrochromen-5-yl 3-methylbut-2-enoate, is a natural compound isolated from various species of fungi, including Antrodia cinnamomea. It has been studied for its potential bioactive properties, including antioxidant, anti-inflammatory, and anticancer activities. Antrodin A’s unique chemical structure and biological properties make it a subject of interest in pharmaceutical and biomedical research for its potential to contribute to the development of novel therapeutic agents.

Reference

1: Yi ZW, Xia YJ, Liu XF, Wang GQ, Xiong ZQ, Ai LZ. Antrodin A from mycelium of Antrodia camphorata alleviates acute alcoholic liver injury and modulates intestinal flora dysbiosis in mice. J Ethnopharmacol. 2020 May 23;254:112681. doi: 10.1016/j.jep.2020.112681. Epub 2020 Feb 19. PMID: 32087320.
2: Xie JQ, Chen YC, Sun ZH, Liu HX, Li SN, Li HH, Gao XX, Zhang WM. [Sesquiterpenoids of endophytic fungus Cerrena sp. from Pogostemon cablin and their cytotoxic activities]. Zhongguo Zhong Yao Za Zhi. 2017 May;42(9):1693-1698. Chinese. doi: 10.19540/j.cnki.cjcmm.20170224.009. PMID: 29082691.
3: He YC, Lu ZH, Shi P, Hao JC, Zhao ZJ, Xie HT, Mao P, Chen SJ. Anti-herpes simplex virus activities of bioactive extracts from Antrodia camphorata mycelia. Antivir Ther. 2016;21(5):377-83. doi: 10.3851/IMP2988. Epub 2015 Aug 27. PMID: 26313544.
4: Phuong do T, Ma CM, Hattori M, Jin JS. Inhibitory effects of antrodins A-E from Antrodia cinnamomea and their metabolites on hepatitis C virus protease. Phytother Res. 2009 Apr;23(4):582-4. doi: 10.1002/ptr.2657. PMID: 19003946.