Apholate

• CAT Number: I022315
• CAS Number: 52-46-0
• Molecular Formula: C12H24N9P3
• Molecular Weight: 387.31
• Purity: 98%
• Synonyms: Pholate; Apholate; AI3-26316; AI326316; AI3 26316
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 2,2,4,4,6,6-hexakis(aziridin-1-yl)-1,3,5-triaza-2lambda5,4lambda5,6lambda5-triphosphacyclohexa-1,3,5-triene
• InChI: InChI=1S/C12H24N9P3/c1-2-16(1)22(17-3-4-17)13-23(18-5-6-18,19-7-8-19)15-24(14-22,20-9-10-20)21-11-12-21/h1-12H2
• InChIKey: PXZAWHSJYIECNQ-UHFFFAOYSA-N
• SMILES: C1CN1P2(=NP(=NP(=N2)(N3CC3)N4CC4)(N5CC5)N6CC6)N7CC7

Apholate（Cat No.:I022315）is a chemical compound that functions as an herbicide, primarily used for weed control in agricultural settings. It works by inhibiting key enzymes involved in the growth and development of plants, particularly targeting the biosynthesis of fatty acids and lipids. Apholate selectively disrupts the metabolic processes in weeds, leading to their death, while having limited effects on crops. Due to its mode of action, apholate is utilized in fields such as rice and cotton farming. However, its potential environmental and toxicological impacts are subject to ongoing evaluation, and its use is carefully regulated in many regions.

Reference

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2: Haqqi TM, Adhami UM. Testicular damage and change in serum LDH isozyme pattern induced by multiple sub-lethal doses of apholate in albino rats. Toxicol Lett. 1982 Jul;12(2-3):199-205. PubMed PMID: 6214049.
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4: Haqqi TM, Adhami UM. Effect of apholate (ENT 26316; NSC 26812) on nucleic acids, total protein content & activity levels of aminotransferases (GOT, GPT), alkaline phosphatase & 5′-nucleotidase in liver of male albino rats. Indian J Exp Biol. 1979 May;17(5):488-92. PubMed PMID: 230151.
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