For research use only. Not for therapeutic Use.
Apilimod(CAT: I011642) is a small molecule inhibitor that targets the enzyme phosphatidylinositol-3-phosphate 5-kinase (PIKfyve), which is involved in the regulation of various cellular processes such as membrane trafficking, cytokinesis, and endosomal trafficking. Apilimod specifically inhibits PIKfyve and thereby reduces the production of phosphatidylinositol-3,5-bisphosphate (PI(3,5)P2), leading to impaired endosomal trafficking and lysosomal function.
| Catalog Number | I011642 |
| CAS Number | 541550-19-0 |
| Synonyms | (E)-4-(6-(2-(3-methylbenzylidene)hydrazinyl)-2-(2-(pyridin-2-yl)ethoxy)pyrimidin-4-yl)morpholine |
| Molecular Formula | C23H26N6O2 |
| Purity | ≥95% |
| Target | Interleukin Related |
| Solubility | >17.9mg/mL in DMSO |
| Storage | Store at -20C |
