Apixaban-13C, d3 is an isotopically labeled form of apixaban, a potent anticoagulant that acts as a direct factor Xa inhibitor. This compound features a carbon-13 isotope and three deuterium atoms, providing enhanced stability and precise isotopic labeling for advanced research applications. Apixaban-13C, d3 is particularly valuable in pharmacokinetic studies, drug metabolism research, and isotope-dilution mass spectrometry. It is essential for investigating the absorption, distribution, metabolism, and excretion (ADME) of apixaban in biological systems. This isotopically labeled compound also serves as a reliable internal standard in analytical chemistry, ensuring accurate and reproducible results in pharmaceutical research and development, particularly in the study of anticoagulant therapies.
| Catalog Number | R060384 |
| CAS Number | 1261393-15-0 |
| Synonyms | 4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide-13C, d3; BMS 562247-01-13C, d3; 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]p |
| Molecular Formula | C25H25N5O4 |
| Purity | 95% |
| Storage | Store at RT |
| IUPAC Name | 7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-1-[4-(trideuteriomethoxy)phenyl]-4,5-dihydropyrazolo[3,4-c]pyridine-3-carboxamide |
| InChI | InChI=1S/C25H25N5O4/c1-34-19-11-9-18(10-12-19)30-23-20(22(27-30)24(26)32)13-15-29(25(23)33)17-7-5-16(6-8-17)28-14-3-2-4-21(28)31/h5-12H,2-4,13-15H2,1H3,(H2,26,32)/i1+1D3 |
| InChIKey | QNZCBYKSOIHPEH-KQORAOOSSA-N |
| SMILES | [2H][13C]([2H])([2H])OC1=CC=C(C=C1)N2C3=C(CCN(C3=O)C4=CC=C(C=C4)N5CCCCC5=O)C(=N2)C(=O)N |
