Apo-Transferrin

• CAT Number: M053459
• CAS Number: 11096-37-0
• Purity: ≥95%

Apo-transferrin (Cat No.: M053459) is the iron-free form of transferrin, a glycoprotein responsible for transporting iron in the blood. It binds to iron in a high-affinity manner and delivers it to cells via transferrin receptors. Apo-transferrin plays a critical role in maintaining iron homeostasis, preventing oxidative stress, and facilitating proper cellular function. It also has potential therapeutic applications, including as a drug delivery vehicle or in treating iron-related disorders such as anemia and hemochromatosis.

Reference

[1]. Baringer SL, et al. Apo- and holo- transferrin differentially interact with ferroportin and hephaestin to regulate iron release at the blood-brain barrier. bioRxiv [Preprint]. 2023 Jan 10:2023.01.10.522344.