ApoA-I mimetic peptide

• CAT Number: I041114
• CAS Number: 221882-20-8
• Molecular Formula: C122H208N30O33
• Molecular Weight: 2623.14
• Purity: ≥95%
• IUPAC Name: (2S)-6-amino-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-5-amino-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-carbamimidamido-2-[[(2S)-2-[[(2S)-2-[[(2S)-3-carboxy-2-[[(2S)-4-methyl-2-[[(2S)-3-methyl-2-[[(2S)-pyrrolidine-2-carbonyl]amino]butanoyl]amino]pentanoyl]amino]propanoyl]amino]-4-methylpentanoyl]amino]-3-phenylpropanoyl]amino]pentanoyl]amino]-4-carboxybutanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-oxobutanoyl]amino]-4-carboxybutanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-carboxybutanoyl]amino]propanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]amino]-5-oxopentanoyl]amino]hexanoyl]amino]-4-methylpentanoyl]amino]hexanoic acid
• InChI: InChI=1S/C122H208N30O33/c1-62(2)51-82(109(172)134-74(33-23-26-46-123)103(166)136-77(38-42-93(126)153)106(169)133-75(34-24-27-47-124)105(168)142-84(53-64(5)6)111(174)140-81(121(184)185)35-25-28-48-125)141-100(163)71(19)132-102(165)78(39-43-95(155)156)138-110(173)83(52-63(3)4)145-112(175)85(54-65(7)8)144-108(171)80(41-45-97(159)160)139-118(181)91(60-94(127)154)149-115(178)88(57-68(13)14)146-113(176)86(55-66(9)10)143-107(170)79(40-44-96(157)158)137-104(167)76(37-30-50-131-122(128)129)135-117(180)90(59-72-31-21-20-22-32-72)148-114(177)87(56-67(11)12)147-119(182)92(61-98(161)162)150-116(179)89(58-69(15)16)151-120(183)99(70(17)18)152-101(164)73-36-29-49-130-73/h20-22,31-32,62-71,73-92,99,130H,23-30,33-61,123-125H2,1-19H3,(H2,126,153)(H2,127,154)(H,132,165)(H,133,169)(H,134,172)(H,135,180)(H,136,166)(H,137,167)(H,138,173)(H,139,181)(H,140,174)(H,141,163)(H,142,168)(H,143,170)(H,144,171)(H,145,175)(H,146,176)(H,147,182)(H,148,177)(H,149,178)(H,150,179)(H,151,183)(H,152,164)(H,155,156)(H,157,158)(H,159,160)(H,161,162)(H,184,185)(H4,128,129,131)/t71-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,99-/m0/s1
• InChIKey: OTFKMDYRWGESRW-BIACLGMUSA-N
• SMILES: C[C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C(C)C)NC(=O)[C@@H]2CCCN2

ApoA-I mimetic peptides（Cat No.:I041114）are synthetic peptides designed to replicate the functional properties of apolipoprotein A-I (ApoA-I), the major protein component of high-density lipoprotein (HDL). These peptides mimic ApoA-I’s ability to promote cholesterol efflux, thereby facilitating the removal of excess cholesterol from cells and tissues, a key process in cardiovascular health. ApoA-I mimetic peptides have been studied for their potential in treating atherosclerosis, cardiovascular diseases, and metabolic disorders by improving lipid metabolism and reducing inflammation.