For research use only. Not for therapeutic Use.
APOL1-IN-1 is a apolipoprotein L1 (APOL1) inhibitor extracted from patent WO2020131807A1 compound 87. APOL1-IN-1 can be used for the research of focal segmental glomerulosclerosis (FSGS) and non-diabetic kidney disease (NDKD)[1].
| Catalog Number | I045225 |
| CAS Number | 2446817-72-5 |
| Synonyms | 3-[2-(4-fluorophenyl)-1H-indol-3-yl]-N-[(3S,4R)-4-hydroxy-2-oxopyrrolidin-3-yl]propanamide |
| Molecular Formula | C21H20FN3O3 |
| Purity | ≥95% |
| InChI | InChI=1S/C21H20FN3O3/c22-13-7-5-12(6-8-13)19-15(14-3-1-2-4-16(14)24-19)9-10-18(27)25-20-17(26)11-23-21(20)28/h1-8,17,20,24,26H,9-11H2,(H,23,28)(H,25,27)/t17-,20+/m1/s1 |
| InChIKey | CNYZYDUBGMRAFP-XLIONFOSSA-N |
| SMILES | C1C(C(C(=O)N1)NC(=O)CCC2=C(NC3=CC=CC=C32)C4=CC=C(C=C4)F)O |
| Reference | [1]. Brodney M, et, al. Inhibitors of apol1 and methods of using same. WO2020131807A1. |
