Apomorphine hydrochloride hemihydrate

• CAT Number: I003503
• CAS Number: 41372-20-7
• Molecular Formula: C17H20ClNO3
• Molecular Weight: 321.8
• Purity: ≥95%
• Synonyms: (R)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol hydrochloride hydrate
• Target: Dopamine Receptor
• Solubility: DMSO: ≥ 31 mg/mL
• Storage: Store at -20C
• SMILES: CN1CCC2=C([C@@]1([H])CC3=C4C(O)=C(O)C=C3)C4=CC=C2.Cl.O

Apomorphine hydrochloride hemihydrate (CAT: I003503) is a non-selective dopamine agonist that activates both D1-like and D2-like receptors in the brain. It exhibits some preference for D2-like receptors, which include D2, D3, and D4 receptors. By stimulating these receptors, apomorphine mimics the action of dopamine, a neurotransmitter involved in regulating movement, cognition, and mood. In the context of Parkinson’s disease, apomorphine’s activation of dopamine receptors helps to compensate for the loss of dopamine-producing cells in the brain, thereby improving motor symptoms associated with the disease.