For research use only. Not for therapeutic Use.
Apramycin sulfate(Cat No.:I004479)is an aminoglycoside antibiotic used in veterinary medicine for the treatment of bacterial infections, particularly in livestock. It inhibits protein synthesis by binding to the bacterial ribosome, thereby preventing the growth of susceptible bacteria. Apramycin sulfate is effective against Gram-negative and some Gram-positive bacteria, including those responsible for respiratory, enteric, and urinary tract infections. Due to its relatively low toxicity in animals, it is commonly employed in farm and aquaculture settings. This compound is essential for maintaining animal health and productivity in agricultural settings.
Catalog Number | I004479 |
CAS Number | 65710-07-8 |
Synonyms | Nebramycin II |
Molecular Formula | C21H43N5O15S |
Purity | ≥95% |
Target | Bacterial |
Solubility | H2O: 25 mg/mL |
Storage | Store at -20°C |
IUPAC Name | (2R,3R,4S,5S,6S)-2-[[(2R,3S,4R,4aR,6S,7R,8aS)-7-amino-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl]oxy-4-hydroxy-3-(methylamino)-2,3,4,4a,6,7,8,8a-octahydropyrano[3,2-b]pyran-2-yl]oxy]-5-amino-6-(hydroxymethyl)oxane-3,4-diol;sulfuric acid |
InChI | InChI=1S/C21H41N5O11.H2O4S/c1-26-11-14(30)18-8(33-20(11)37-21-16(32)13(29)10(25)9(4-27)34-21)3-7(24)19(36-18)35-17-6(23)2-5(22)12(28)15(17)31;1-5(2,3)4/h5-21,26-32H,2-4,22-25H2,1H3;(H2,1,2,3,4)/t5-,6+,7-,8+,9-,10-,11+,12+,13+,14-,15-,16-,17-,18+,19+,20-,21-;/m1./s1 |
InChIKey | WGLYHYWDYPSNPF-RQFIXDHTSA-N |
SMILES | CN[C@H]1[C@H]([C@@H]2[C@H](C[C@H]([C@H](O2)O[C@@H]3[C@H](C[C@H]([C@@H]([C@H]3O)O)N)N)N)O[C@@H]1O[C@@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)N)O)O)O.OS(=O)(=O)O |
Reference | <p style=/line-height:25px/> |