For research use only. Not for therapeutic Use.
AQ-13 dihydrochloride is an aminoquinoline antimalarial agent that is effective against drug-resistant strains of Plasmodium falciparum.
Slight decreases in the PCE/RBC ratio are observed in male and female rats treated with CQ and in females only treated with AQ-13; however, none of these changes is statistically significant[1].
Catalog Number | I002644 |
CAS Number | 169815-40-1 |
Synonyms | N-(7-chloroquinolin-4-yl)-N’,N’-diethylpropane-1,3-diamine;dihydrochloride |
Molecular Formula | C16H24Cl3N3 |
Purity | ≥95% |
InChI | InChI=1S/C16H22ClN3.2ClH/c1-3-20(4-2)11-5-9-18-15-8-10-19-16-12-13(17)6-7-14(15)16;;/h6-8,10,12H,3-5,9,11H2,1-2H3,(H,18,19);2*1H |
InChIKey | ZNHBPWZRWNFJPN-UHFFFAOYSA-N |
SMILES | CCN(CC)CCCNC1=C2C=CC(=CC2=NC=C1)Cl.Cl.Cl |
Reference | [1]. Riccio ES, et al. Genetic toxicology testing of the antimalarial drugs chloroquine and a new analog, AQ-13. Environ Mol Mutagen. 2001;38(1):69-79. |