AR-7

For research use only. Not for therapeutic Use.

  • CAT Number: I002682
  • CAS Number: 80306-38-3
  • Molecular Formula: C15H12ClNO
  • Molecular Weight: 257.71
  • Purity: ≥95%
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AR7 (Cat No.:I002682) is a retinoic acid receptor alpha (RARα) antagonist. Ar7 is a CMA booster for biological studies of retinoic acid derivative-mediated chemical regulation of autophagy in chaperone cells. If you need, please contact us in time, and we will reply to you as soon as possible within 24 hours.


Catalog Number I002682
CAS Number 80306-38-3
Synonyms

AR-7; AR 7; AR7; Atypical retinoid 7.;7-Chloro-3-(p-tolyl)-2H-benzo[b][1,4]oxazine

Molecular Formula C15H12ClNO
Purity ≥95%
Solubility Soluble in DMSO
Storage Sealed in dry,2-8°C
IUPAC Name 7-chloro-3-(4-methylphenyl)-2H-1,4-benzoxazine
InChI InChI=1S/C15H12ClNO/c1-10-2-4-11(5-3-10)14-9-18-15-8-12(16)6-7-13(15)17-14/h2-8H,9H2,1H3
InChIKey MVOZLTFXYGHZPM-UHFFFAOYSA-N
SMILES CC1=CC=C(C=C1)C2=NC3=C(C=C(C=C3)Cl)OC2
Reference

</br>1:Physiological adaptations and tolerance towards higher concentration of selenite (Se(+4)) in Enterobacter sp. AR-4, Bacillus sp. AR-6 and Delftia tsuruhatensis AR-7. Prakash D, Pandey J, Tiwary BN, Jain RK.Extremophiles. 2010 May;14(3):261-72. doi: 10.1007/s00792-010-0305-8. Epub 2010 Mar 16. PMID: 20232096 </br>2:Natural and experimental Salmonella arizonae 18:z4,z32 (Ar. 7:1,7,8) infection in broilers. Bacteriological and histopathological survey of eye and brain lesions. Silva EN, Hipolito O, Grecchi R.Avian Dis. 1980 Jul-Sep;24(3):631-6. PMID: 7447834

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