Arachidonic Acid

• CAT Number: R001993
• CAS Number: 506-32-1
• Molecular Formula: C20H32O2
• Molecular Weight: 304.474
• Purity: 99%
• Synonyms: (5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraenoic Acid; (all-Z)-5,8,11,14-Eicosatetraenoic Acid; 5,8,11,14-all-cis-EicosaA765000, tetraenoicmmunocytophyte; Immunocytophyte; all-cis-5,8,11,14-Eicosatetraenoic Acid; cis-5,8,11,14-Eicosatetraenoic Acid; ?
• Target: Metabolic Enzyme/Protease
• Appearance: Liquid
• Storage: -20°C
• IUPAC Name: (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid
• InChI: InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15-
• InChIKey: YZXBAPSDXZZRGB-DOFZRALJSA-N
• SMILES: CCCCCC=CCC=CCC=CCC=CCCCC(=O)O

Arachidonic acid (Cat.No:R001993) is an unsaturated, essential fatty acid. It is found in animal and human fat as well as in the liver, brain, and glandular organs, and is a constituent of animal phosphatides. It is formed by the synthesis from dietary linoleic acid and is a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes.

Reference

1. H. Katsuki and S. Okuda “Arachidonic acid as a neurotoxic and neurotrophic substance” Prog Neurobiol, vol. 46(6) pp. 607-636, 19952. R. Sanchez-Mejia and L. Mucke “Phospholipase A2 and arachidonic acid in Alzheimer/'s disease” Biochim Biophys Acta, vol. 1801(8) pp. 784-790, 20103. E. Bates “Eicosanoids, fatty acids and neutrophils: their relevance to the pathophysiology of disease” Prostaglandins Leukot Essent Fatty Acids,vol. 53 pp.75–86, 19954. L. Levine “Proteasome inhibitors: Their effects on arachidonic acid release from cells in culture and arachidonic acid metabolism in rat livercells” BMC Pharmacology, vol. 4(15), 2004