For research use only. Not for therapeutic Use.
Arg-Gly-Asp-Cys TFA is the binding motif of fibronectin to cell adhesion molecules. Arg-Gly-Asp-Cys TFA can inhibit platelet aggregation and fibrinogen binding[1].
Arg-Gly-Asp-Cys-functionalized chitosan (0.25-1 mg/mL; 2-7 days) favors cell growth and an increase in cellular proliferation compared to the control cells (viability >140%)[1].
Arg-Gly-Asp-Cys-functionalizes chitosan derivatives exhibit in vitro wound healing properties by enhancing fibroblast proliferation and adhesion[1].
| Catalog Number | I044767 |
| CAS Number | 2171504-22-4 |
| Synonyms | (3S)-3-[[2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]-4-[[(1R)-1-carboxy-2-sulfanylethyl]amino]-4-oxobutanoic acid;2,2,2-trifluoroacetic acid |
| Molecular Formula | C15H27N7O7S.xC2HF3O2 |
| Purity | ≥95% |
| InChI | InChI=1S/C15H27N7O7S.C2HF3O2/c16-7(2-1-3-19-15(17)18)12(26)20-5-10(23)21-8(4-11(24)25)13(27)22-9(6-30)14(28)29;3-2(4,5)1(6)7/h7-9,30H,1-6,16H2,(H,20,26)(H,21,23)(H,22,27)(H,24,25)(H,28,29)(H4,17,18,19);(H,6,7)/t7-,8-,9-;/m0./s1 |
| InChIKey | AJFGGKXZCJCXNM-YWUTZLAHSA-N |
| SMILES | C(CC(C(=O)NCC(=O)NC(CC(=O)O)C(=O)NC(CS)C(=O)O)N)CN=C(N)N.C(=O)(C(F)(F)F)O |
| Reference | [1]. Patrulea V, et, al. Peptide-decorated chitosan derivatives enhance fibroblast adhesion and proliferation in wound healing. Carbohydr Polym. 2016 May 20;142:114-23. |
