(ARG6,D-TRP7,9,N-ME-PHE8)-SUBSTANCE P (6-11)

• CAT Number: M021812
• CAS Number: 115150-59-9
• Molecular Formula: C49H66N12O6S
• Molecular Weight: 951.20
• Purity: ≥95%
• Synonyms: (S)-N-((5S,8S,11R,14S,17R)-11-((1H-indol-3-yl)methyl)-14-benzyl-5-carbamoyl-18-(1H-indol-3-yl)-8-isobutyl-15-methyl-7,10,13,16-tetraoxo-2-thia-6,9,12,15-tetraazaoctadecan-17-yl)-2-amino-5-((diaminomethylene)amino)pentanamide
• Target: Tachykinin
• Solubility: Soluble to 1 mg/ml in sterile water
• Storage: Desiccate at -20C
• IUPAC Name: (2S)-2-[[(2R)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]-methylamino]-3-phenylpropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-N-[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]-4-methylpentanamide
• InChI: InChI=1S/C49H66N12O6S/c1-29(2)23-39(45(64)57-38(43(51)62)20-22-68-4)58-46(65)40(25-31-27-55-36-18-10-8-15-33(31)36)59-47(66)42(24-30-13-6-5-7-14-30)61(3)48(67)41(26-32-28-56-37-19-11-9-16-34(32)37)60-44(63)35(50)17-12-21-54-49(52)53/h5-11,13-16,18-19,27-29,35,38-42,55-56H,12,17,20-26,50H2,1-4H3,(H2,51,62)(H,57,64)(H,58,65)(H,59,66)(H,60,63)(H4,52,53,54)/t35-,38-,39-,40+,41+,42-/m0/s1
• InChIKey: CUCSSYAUKKIDJV-FAXBSAIASA-N
• SMILES: CC(C)C[C@@H](C(=O)N[C@@H](CCSC)C(=O)N)NC(=O)[C@@H](CC1=CNC2=CC=CC=C21)NC(=O)[C@H](CC3=CC=CC=C3)N(C)C(=O)[C@@H](CC4=CNC5=CC=CC=C54)NC(=O)[C@H](CCCN=C(N)N)N

(ARG6,D-TRP7,9,N-ME-PHE8)-Substance P (6-11)（Cat No.:M021812）is a synthetic peptide analog of the neuropeptide Substance P, specifically modified to enhance stability and receptor binding. Substance P is involved in pain transmission, inflammation, and neurogenic processes by acting on neurokinin-1 (NK1) receptors. This modified version retains the core functional sequence (6-11) while incorporating substitutions like D-tryptophan and N-methylphenylalanine to resist enzymatic degradation. It is often used in research to study pain pathways, receptor interactions, and potential therapeutic applications in modulating neuroinflammatory and pain-related conditions.