ARL 67156 Trisodium Salt

• CAT Number: R014287
• CAS Number: 1021868-83-6
• Molecular Formula: C15H21Br2N5O12P3.3Na
• Molecular Weight: 785.06
• Purity: ≥95%
• Synonyms: N,N-diethyl-5’-Adenylic Acid 5’-anhydride with P,P’-(Dibromomethylene)bis[phosphonic Acid]Sodium Salt
• Target: NTPDase
• Solubility: Soluble to 20 mM in sterile water
• Storage: Desiccate at -20C
• InChI: InChI=1S/C15H24Br2N5O12P3/c1-4-21(5-2)11-8-12(19-6-18-11)22(7-20-8)13-9(23)10(24)14(32-13)33-37(30,31-3)34-36(28,29)15(16,17)35(25,26)27/h6-7,9-10,13-14,23-24H,4-5H2,1-3H3,(H,28,29)(H2,25,26,27)/t9-,10+,13-,14-,37?/m1/s1
• InChIKey: FGVPLSHBVJFZKC-WHIQPUKWSA-N
• SMILES: O=P(C(Br)(P(O)(O)=O)Br)(OP(O[C@H]1O[C@@H](N2C=NC3=C(N(CC)CC)N=CN=C23)[C@H](O)[C@@H]1O)(OC)=O)O

ARL 67156 is a research compound used experimantally as the trisodium salt. It is an inhibitor of ecto-ATPase activity. Structurally, ARL 67156 is an analogue of ATP and therefore competes with substrate at the enzyme.

Reference

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