For research use only. Not for therapeutic Use.
ARN 077 enantiomer (19) is the less active enantiomer of ARN 077, with an IC50 of 3.53 μM for rat NAAA[1].
| Catalog Number | I045535 |
| CAS Number | 1439366-88-7 |
| Synonyms | 5-phenylpentyl N-[(2R,3S)-2-methyl-4-oxooxetan-3-yl]carbamate |
| Molecular Formula | C16H21NO4 |
| Purity | ≥95% |
| InChI | InChI=1S/C16H21NO4/c1-12-14(15(18)21-12)17-16(19)20-11-7-3-6-10-13-8-4-2-5-9-13/h2,4-5,8-9,12,14H,3,6-7,10-11H2,1H3,(H,17,19)/t12-,14+/m1/s1 |
| InChIKey | PTVDTLVLQXSSEC-OCCSQVGLSA-N |
| SMILES | CC1C(C(=O)O1)NC(=O)OCCCCCC2=CC=CC=C2 |
| Reference | [1]. Stefano Ponzano, et al. Synthesis and structure-activity relationship (SAR) of 2-methyl-4-oxo-3-oxetanylcarbamic acid esters, a class of potent N-acylethanolamine acid amidase (NAAA) inhibitors. J Med Chem. 2013 Sep 12;56(17):6917-34. |
